The connection between vitamin D levels and the presence of IBD has been well investigated. Several studies have found that individuals with vitamin D deficiency are at a greater risk of developing IBD. Further, in some studies, up to 60-70% of individuals with IBD have vitamin D insufficiency. In those with IBD, a vitamin D deficiency makes them more susceptible to cancer, especially colon cancer.
Low vitamin D levels also put those suffering from IBD at a higher risk for Clostridium difficile infection. Vitamin D deficiency impacts the severity of IBD too. People with Crohn’s disease and ulcerative colitis tend to have a more aggressive form of the disease if they have a vitamin D deficiency.
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References
- Tabatabaeizadeh, Seyed-Amir et al. “Vitamin D, the gut microbiome and inflammatory bowel disease.” Journal of research in medical sciences: The official journal of Isfahan University of Medical Sciences vol. 23 75. 23 Aug. 2018, doi:10.4103/jrms.JRMS_606_17
- Ananthakrishnan, Ashwin N. “Vitamin D and Inflammatory Bowel Disease.” Gastroenterology & Hepatology vol. 12,8 (2016): 513-515.
- Baidoun, Firas, et al. “Association Between Vitamin D Deficiency and Inflammatory Bowel Disease (IBD).” The American Journal of Gastroenterology, vol. 114, no. 1, Oct. 2019, doi:10.14309/01.ajg.0000592612.35370.0d.
- Rhodes, Jonathan. “Research Study: Vitamin D and IBD.” Crohn’s & Colitis UK, 12 Oct. 2016, www.crohnsandcolitis.org.uk/news/research-study-vitamin-d-and-ibd.
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