The IDK® PMN Elastase ELISA (Stool) is an enzyme immunoassay intended for the quantitative determination of PMN elastase in stool.

PMN-elastase from human polymorphonuclear granulocytes is a glycoprotein of 30 kDa and belongs to the group of serine proteases. Active PMN-elastase is released from the azurophil granula of neutrophil granulocytes after irritation or disintegration. Determining PMN-Elastase in stool records inflammatory reactions where neutrophils are involved. Especially in Crohn´s disease, the inflammatory process goes hand in hand with increased phagocytic activity and the biological decay of these cells. It thus leads to an increased release of PMN-Elastase and other lysosomal enzymes.

This is the RUO version of Immundiagnostik part number K 6840. The IDK® PMN Elastase ELISA (Stool) is for research use only. Not for use in diagnostic procedures.