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IDK® α1-Antitrypsin ELISA

Item #: KR6750 Categories: ,

$425.00

In Stock

Method: ELISA
Sample Type (Matrix): Stool
Sample Volume: 15 mg
Species: Human
Incubation time: 2h 15m
Standard Range: 3.3-90 µg/l
Size: 96 wells
Regulatory Status: For research use only in the U.S.
Kit Manual: Download

α1-Antitrypsin is released during inflammatory processes by polymorphonuclear neutrophilic granulocytes (PMN) to reduce the proteolytic activity of PMN elastase in the inflammation region. α1-Antitrypsin is also a serine proteinase inhibitor, thus it acts as both a regulatory and anti-inflammatory protein. The measurement of fecal α1-Antitrypsin concentration is used to evaluate and monitor chronic inflammatory intestinal diseases because it is a marker for intestinal protein loss and permeability as well as intestinal inflammation.

The IDK® α1-Antitrypsin ELISA is an enzyme immunoassay intended for the quantitative determination of α1-antitrypsin in stool.

The IDK® α1-Antitrypsin ELISA is compatible with our IDK Extract® Stool Sample Preparation System.

Indications

  • Monitor enteric protein loss and intestinal permeability
  • Evaluation and monitoring of chronic inflammatory intestinal diseases

Features

  • The α1-Antitrypsin concentration obtained by the ELISA is on average 30% higher than the corresponding values from the radial immunodiffusion measurements.
  • Only the ELISA system detected α1-Antitrypsin in cell culture supernatants.
  • The ELISA system can recognize hepatic and enteral α1-antitrypsin forms.
  • The combination of two specific antibodies largely eliminates the possibility of false-negative results.

If your lab is testing at high volumes, the IDK® α1-Antitrypsin ELISA is also available in a customized bulk pack (20 plates).

This is the RUO version of Immundiagnostik part number K 6750. For research use only. Not for use in diagnostic procedures.

Additional information

Weight35.5 oz
Dimensions6.5 × 10 × 4.5 in
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